- Altana Pharma
 - Specialising in products for gastrointestinal, cardiovascular, respiratory tract diseases, and contrast agents. Formerly Byk Gulden. - Boehringer Ingelheim
- Manufactures and markets pharmaceuticals, prescription medicines, and consumer health care products along with products for the industrial and animal health markets.
- Merck KGaA
- Conducts its internationally oriented business in the three business sectors of pharmaceuticals, laboratory, and speciality chemicals.
- Merz
- Develops products for health and beauty.
- ratiopharm International
- Develops and produces high-quality generic drugs globally.
- Schering
- Specialises in fertility control and hormone therapy, diagnostics and radiopharmaceuticals, dermatology, and specialised therapeutics for severe diseases.
- Schwarz Pharma
- Develops and markets innovative drugs for unmet medical needs with focus on CNS, urology, and cardiovascular diseases.
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